Brechtel’s fully controlled and integrated Particle-into-Liquid Sampler (PILS) can be set-up in the field within a few minutes, allowing unattended aerosol sampling for at least a couple of days. Because of its flexibility, we have used Brechtel’s PILS extensively since 2007 in many online and offline configurations. At our request, BMI also developed a version of their software enabling the use of its PILS to work online with several instruments at the same time. So far, we have successfully used Brechtel’s PILS to feed (both online and simultaneously) two ion chromatography systems (anions/cations) and a TOC analyzer (Water Soluble Organic Carbon) during intensive EU-FP7-MEGAPOLI field experiments in Paris in 2009 and 2010. In 2011, we successfully coupled Brechtel’s PILS with a Liquid Chromatography / Mass Spectrometer (LC-MS/MS) to perform real-time (2.5 minutes) ppb-level atmospheric measurements of aerosol organic tracers (levoglucosan) in fine aerosols during a one-month experiment.